发明名称 |
Monoclonal antibodies, synthetic and biotechnological derivatives thereof actingas ngf-antagonist molecules |
摘要 |
Monoclonal antibodies, synthetic and biotechnological derivatives thereof (ScFv or others) are able to recognise the NGF high affinity receptor, TrkA, and act as NGF-antagonist molecules. Pharmacological compositions for therapy, gene therapy, diagnostics of neurological pathologies are also described. Transgenic animal models to study such pathologies are also described. |
申请公布号 |
AU5101900(A) |
申请公布日期 |
2000.12.18 |
申请号 |
AU20000051019 |
申请日期 |
2000.05.26 |
申请人 |
SIRS SOCIETA ITALIANA PER LA RICERCA SCIENTIFICA SRL |
发明人 |
MICHAL M. NOVAK |
分类号 |
A01K67/027;A61K35/76;A61K38/22;A61K39/395;A61K48/00;A61K49/04;A61P25/04;A61P29/00;A61P35/00;C07K16/28;C12N1/15;C12N1/19;C12N5/10;C12N15/02;C12P21/08 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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