摘要 |
<p>A column (20) is provided for use in high performance liquid systems. The column (20) has a bore (50) passing therethrough with an inlet (52) larger than an outlet (54). The side wall (56) of the bore (50) tapers as it extends between the inlet (52) and the outlet (54). The tapering bore (50) is packed with a chromatographic separation medium held within the tapering bore (50) by an inlet frit (38) adjacent an inlet (52) and an outlet frit (48) adjacent the outlet (54). The tapered bore column (20) can be substituted for standard cylindrical bore columns with high performance liquid chromatography systems to increase sample component resolution per unit time.</p> |