发明名称 |
NASAL PREPARATIONS |
摘要 |
Pernasal preparations characterized by containing a compound of general formula (I) having an Na/H exchange inhibiting activity or a salt thereof exhibit excellent bioabsorbability and an Na/H exchange inhibiting activity superior to those of peroral preparations, thus being useful as preventive and/or therapeutic agents for ischemic heart diseases such as myocardial infarct and arrhythmia: wherein A is an optionally substituted five- or six- membered aromatic heterocycle; B is an optionally substituted five- or six- membered aromatic homo- or hetero-cycle; R1 is hydrogen, hydroxyl, or lower alkyl; and n is 0 or 1.
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申请公布号 |
CA2375702(A1) |
申请公布日期 |
2000.12.14 |
申请号 |
CA20002375702 |
申请日期 |
2000.06.01 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
SHIRAISHI, MITSURU;FUKUMOTO, SHOJI;TAKADA, SHIGEYUKI;MISAKI, MASAFUMI |
分类号 |
A61K9/00;A61K31/47;A61P9/04;A61P9/06;A61P9/10;A61P9/14;C07D215/38;(IPC1-7):C07D215/38;A61K9/08;A61K9/14 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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