PRODUCTION OF POWDER FORMULATIONS

摘要

A method for producing a powder comprises the steps of: charging a vessel with a mixture of at least two solid components. At least one of the solid components comprises a polymeric resin. The vessel charged with a fluid in which the polymeric resin and preferably the other components of the mixture is not substantially soluble. The fluid is selected such that the density of the fluid can be adjusted upon adjustment of temperature and pressure in the vessel to enable creation of a suspension of the mixture within the vessel upon agitation of the contents of the vessel. The temperature is maintained above the glass transition temperature of the polymeric resin in the fluid. The pressure of the fluid is adjusted such that the density of the fluid enables creation of the suspension of the mixture within the vessel upon agitation of the contents of the vessel. The contents of the vessel is agitated to create the suspension. The temperature is then reduced to a temperature below the glass transition temperature of the polymeric resin component in the fluid.