| 摘要 |
PROBLEM TO BE SOLVED: To obtain a 4-acetylaminobenzenesulfonylazide in a high yield by reacting acetylaminobenzenesulfonyl chloride with an inorganic azide salt in the presence of an amine salt catalyst in a non-aqueous organic solvent. SOLUTION: This method for producing a compound of formula II comprises reacting (A) 4-acetylaminobenzenesulfonyl chloride of formula I with (B) an inorganic azide salt of the formula: M(N3)n [M is an alkali(ne earth) metal; (n) is 1 or 2], such as sodium azide, in the presence of an amine salt catalyst, preferably triethylamine hydrochloride, in a solvent (for example, acetonitrile) dissolving the 4-acetylaminobenzenesulfonyl chloride preferably at 20 to 60 deg.C for 1 to 120 hr. The components B and C are used in amounts of 1.0 to 1.1 moles and 0.002 to 0.02 mole, respectively, per mole of the component A, and the component D is preferably used in an amount of 1 to 10 ml per g of the component A. |
