发明名称 NOVEL USE OF 1-[4-(5-CYANOINDOL-3-YL)BUTYL]-4-(2-CARBAMOYL-BENZOFURAN-5-YL)-PIPERAZINE AND ITS PHYSIOLOGICALLY ACCEPTABLE SALTS
摘要 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine or a physiologically acceptable salt thereof is used for the manufacture of a medicament for the treatment of sub-type anxiety disorders chosen from the s ub- types panic disorder with or without agoraphobia, agoraphobia, obsessive- compulsive spectrum disorders, social phobia, posttraumatic stress disorder, acute stress indication or generalized-anxiety disorder, bipolar disorders, mania, dementia, substance-related disorders, sexual dysfunctions, eating disorders, obesity, anorexia and fibromyalgia. A preferred salt is 1-[4-(5- cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine hydrochloride.
申请公布号 CA2372668(A1) 申请公布日期 2000.12.07
申请号 CA20002372668 申请日期 2000.05.16
申请人 MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG 发明人 BARTOSZYK, GERD;SEYFRIED, CHRISTOPH;VAN AMSTERDAM, CHRISTOPHER;BOTTCHER, HENNING;SEDMAN, EWEN
分类号 C07D405/12;A61K31/00;A61K31/495;A61K31/496;A61P1/14;A61P3/04;A61P15/10;A61P21/00;A61P25/00;A61P25/22;A61P25/28;A61P29/00;(IPC1-7):A61K31/495 主分类号 C07D405/12
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