摘要 |
<p>Mammal transcription factor APRF, process for the preparation of it, DNAs encoding the said product, replication and expression vector comprising the said DNA, host cells transformed or tranfected with the said replication and expression vector, evaluating and screening method for searching an inhibitory agent on the function of APRF and an inhibitory agent against the function of the said APRF. The peptide of the present invention (APRF) may be useful for complement or suppression of the function of APRF, screening an inhibitory agent against the function of APRF. Inhibiting agent containing the said product as active ingredient of the present invention may be also useful for treatment of diseases related cytokine such as IL-6 i.e. inflammatory diseases.</p> |