发明名称 |
ANTITUMOR DIBENZOFLUORENE DERIVATIVES |
摘要 |
Dibenzofluorene derivatives having a formula selected from the group consisting of (I) and (II), and salts thereof have antitumor activity. At least one of R1-R13 in formula (I) or R1-R121 in formula (II) is -R14Z. R14 is a substituted or unsubstituted amino or amido group having from 1-12 carbon atoms, and Z is a substituted or unsubstituted heterocyclic group having from 1-12 carbon atoms. The remainder of R1-R13 in formula (I) or R1-R12 in formula (II) are independently selected from the group consisting of hydrogen, hydroxyl, halogen, nitro, substituted or unsubstituted amino or amido groups having from 1-12 carbon atoms, and alkyl groups having 1-12 carbon atoms.
|
申请公布号 |
WO0032583(A9) |
申请公布日期 |
2000.11.30 |
申请号 |
WO1999US27691 |
申请日期 |
1999.11.22 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
BECKER, FREDERICK, F.;BANIK, BIMAL, K. |
分类号 |
C07D295/18;A01N43/60;A61K31/135;A61K31/4453;A61K31/495;A61K31/535;A61P35/00;C07D211/06;C07D241/04;C07D265/30;C07D279/12;C07D295/00;(IPC1-7):C07D295/18;A61K31/445 |
主分类号 |
C07D295/18 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|