| 发明名称 |
OLIGOPEPTIDE AND CONJUGATE THEREOF SELECTIVELY CLEAVED BY PROSTATE SPECIFIC ANTIGEN |
| 摘要 |
The invention relates to an oligopeptide in the shape of Semenogelin I peptidic fragment or a Semenogelin I modified peptidic fragment and oligomers of said oligopeptides, recognized and proteolytically cleaved by free prostate specific antigen and oligomers of said oligopeptides, and to the conjugate of said oligopeptide, used in the treatment of prostate cancer.
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| 申请公布号 |
RO116198(B1) |
申请公布日期 |
2000.11.30 |
| 申请号 |
RO19960002483 |
申请日期 |
1995.06.07 |
| 申请人 |
MERCK & CO, INC, RAHWAY |
发明人 |
DEFEO JONES DEBORAH;FENG DONG-MEI;GARSKY VICTOR M;JONES RAYMOND E;OLIFF ALLEN I |
| 分类号 |
G01N33/566;A61K31/195;A61K38/00;A61K38/08;A61K47/48;A61P13/08;A61P35/00;A61P43/00;C07H15/24;C07K7/06;C07K7/08;C07K14/47;C07K17/08;C12Q1/37;G01N33/574;(IPC1-7):C07K1/00;C07K7/00;C07K14/00;C12Q1/00 |
主分类号 |
G01N33/566 |
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