发明名称 |
Process for making a cyclodextrin |
摘要 |
Sulfoalkyl ether cyclodextrins are produced by a process of treating an unsubstituted cyclodextrin starting material with an alkyl sultone in the presence of a base. The base is added in a stepwise, pH controlled manner so that substantially the entire initial charge of cyclodextrin starting material is at least partially reacted. Additional base is then added to complete the reaction, and residual alkyl suftone is destroyed. The product advantageously contains low levels of both residual cyclodextrin and residual alkyl sultone.
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申请公布号 |
US6153746(A) |
申请公布日期 |
2000.11.28 |
申请号 |
US19980106983 |
申请日期 |
1998.06.29 |
申请人 |
PFIZER INC. |
发明人 |
SHAH, BHARAT K.;SKLAVOUNOS, CONSTANTINE |
分类号 |
C08B37/16;(IPC1-7):C07H1/00 |
主分类号 |
C08B37/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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