发明名称 COMPLEX FORMING HYDROXYAPATITE ON SILICIC ACID COMPOUND AND ITS PRODUCTION
摘要 PROBLEM TO BE SOLVED: To obtain a composite having excellent heat resistance, solvent resistance and strong mechanical strength by alternately immersing a base material composed of a silicic acid compound in an aqueous solution of a calcium salt and in an aqueous solution of a phosphate and forming a bone-like hydroxyapatite having C-axis orientation on its surface. SOLUTION: A base material composed of a silicic acid compound having >=about 100 nm particle diameter, width, etc., (silica, calcium silicate, aluminum silicate, etc.), is alternately immersed in an aqueous solution of a calcium salt (calcium chloride, etc.), and in an aqueous solution of a phosphate (disodium hydrogenphosphate, etc.), and a bone-like hydroxyapatite having C-axis orientation is formed to give a composite. The immersion is repeated about >=6 times, the immersion time is about 20-60 minutes, the temperature of the aqueous solution is about 5-70 deg.C and the pH of the aqueous solution is 6-9, preferably 7.4. The concentration of the aqueous solution may be from about 0.1 mmol to a saturated solution and is preferably >= about 20 mmol in order to quickly form hydroxyapatite.
申请公布号 JP2000327313(A) 申请公布日期 2000.11.28
申请号 JP19990170111 申请日期 1999.05.12
申请人 AKASHI MITSURU;SUZUKI YUSHI KOGYO KK 发明人 AKASHI MITSURU;TAGUCHI TETSUSHI;KUROKI OSAMU
分类号 A61L27/00;C01B25/32;C01B33/12 主分类号 A61L27/00
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