Use if bis(amidinobenzamidazoles) in inhibiting retroviral integrases and treating HIV infection

摘要

Method for inhibiting retroviral integrase and HIV infection by administering a compound, preferably 1,2-bis[5-amidino-2-benzimidazolyl]methane, according to Formula (I), wherein: R1 and R2 are each independently H or lower alkyl, or R1 and R2 together represent -(CH2)m- (m is from 2 to 4) R3 is H or lower alkyl and X is C1-2 saturated or unsaturated alkyl containing up to one double bond