| 发明名称 |
IDENTIFICATION OF GLYCOSPHINGOLIPIDS THAT PROMOTE HIV-1 ENTRY INTO CELLS |
| 摘要 |
<p>The invention is related to the discovery of cofactors that promote CD4-dependent HIV-1 fusion and entry. More specifically, disclosed herein are biotechnological tools, diagnostics, prophylactics, therapeutics and methods of use of the foregoing for the treatment and prevention of HIV-1 infection that exploit interactions between gp120-gp41 and glycosphingolipids.</p> |
| 申请公布号 |
WO0029556(A3) |
申请公布日期 |
2000.11.23 |
| 申请号 |
WO1999US27341 |
申请日期 |
1999.11.16 |
| 申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;BLUMENTHAL, ROBERT;PURI, ANU;HUG, PETER |
发明人 |
BLUMENTHAL, ROBERT;PURI, ANU;HUG, PETER |
| 分类号 |
A61K31/395;A61K31/70;A61K38/16;A61K38/46;C07K16/40;C12N7/00;C12Q1/18;G01N33/50;G01N33/569;(IPC1-7):C12N5/12;A61M1/16;C12N5/06;A61P31/18;A61K38/17;A61K48/00;A61K39/395 |
主分类号 |
A61K31/395 |
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