发明名称 |
LAWSONIA DERIVED GENE AND RELATED FLGE POLYPEPTIDES, PEPTIDES AND PROTEINS AND THEIR USES |
摘要 |
The present invention relates generally to therapeutic compositions for the treatment and/or prophylaxis of intestinal disease conditions in animals and birds caused or exacerbated by Lawsonia intracellularis or similar or otherwise related microorganism. In particular, the present invention provid es a novel gene derived from Lawsonia intracellularis which encodes an immunogenic FlgE peptide, polypeptide or protein that is particularly useful as an antigen in vaccine preparation for conferring humoral immunity against Lawsonia intracellularis and related pathogens in animal hosts. The present invention is also directed to methods for the treatment and/or prophylaxis o f such intestinal disease conditions and to diagnostic agents and procedures f or detecting Lawsonia intracellularis or similar or otherwise related microorganisms.
|
申请公布号 |
CA2372098(A1) |
申请公布日期 |
2000.11.23 |
申请号 |
CA20002372098 |
申请日期 |
2000.05.11 |
申请人 |
PFIZER PRODUCTS INC.,;AGRICULTURE VICTORIA SERVICES PTY LTD;AUSTRALIAN PORK LIMITED |
发明人 |
PANACCIO, MICHAEL;ROSEY, EVERETT LEE;PARSONS, JIM;HASSE, DETLEF;SINISTAJ, MERI;ANKENBAUER, ROBERT GERARD |
分类号 |
G01N33/53;A61K38/00;A61K39/00;A61K39/02;A61P1/00;A61P29/00;A61P35/00;C07K14/195;C07K14/205;C07K16/12;C12N15/09;C12P21/08;C12Q1/68;G01N33/566;G01N33/569;G01N33/577;(IPC1-7):C12N15/31;C07H21/04;C12N15/10 |
主分类号 |
G01N33/53 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|