| 发明名称 |
A STABLE PHARMACEUTICAL COMPOSITION OF TERFENADINE AND IBUPROFEN |
| 摘要 |
<p>PCT No. PCT/US94/10972 Sec. 371 Date Jul. 3, 1996 Sec. 102(e) Date Jul. 3, 1996 PCT Filed Sep. 28, 1994 PCT Pub. No. WO95/11677 PCT Pub. Date May 4, 1995The present invention is directed to a chemically stable pharmaceutical composition containing ibuprofen in combination with terfenadine, wherein the oxidation of terfenadine to terfenadone is prevented by the presence in the composition of an alpha -hydroxy carboxylic acid.</p> |
| 申请公布号 |
EP0725639(B1) |
申请公布日期 |
2000.11.15 |
| 申请号 |
EP19940929374 |
申请日期 |
1994.09.28 |
| 申请人 |
MERRELL PHARMACEUTICALS INC. |
发明人 |
ERTEL, KEITH D.;LONG, DAVID F. |
| 分类号 |
A61K47/12;A61K31/19;A61K31/445;(IPC1-7):A61K31/445 |
主分类号 |
A61K47/12 |
| 代理机构 |
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代理人 |
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| 地址 |
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