发明名称 |
METHODS FOR INCREASING T CELL PROLIFERATION |
摘要 |
<p>The invention provides methods and compositions for increasing T cell proliferation using tryptophan enhancing agents. T cell proliferation can be increased in vitro by addition of tryptophan enhancing agents to T cell culture, or in vivo by administration of tryptophan enhancing agents. Also provided are methods for diagnosing and treating disorders characterized by constitutive expression of indoleamine-2,3-dioxygenase. Compositions and apparatus relating to the methods also are provided.</p> |
申请公布号 |
WO0066764(A1) |
申请公布日期 |
2000.11.09 |
申请号 |
WO2000US12118 |
申请日期 |
2000.05.03 |
申请人 |
LUDWIG INSTITUTE FOR CANCER RESEARCH |
发明人 |
VAN DEN EYNDE, BENOIT;BILSBOROUGH, JANINE;BOON-FALLEUR, THIERRY |
分类号 |
A61K31/00;A61K31/343;A61K31/381;A61K31/405;C12Q1/26;C12Q1/68;G01N33/574;(IPC1-7):C12Q1/26 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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