| 摘要 |
The instant invention provides an apparatus, a kit and a method for treating a tumor in an extremity of a patient. The method first includes: providing a first catheter designed, sized and dimensioned for percutaneous insertion into the specific vein or portion of vein of the extremity receiving the blood from the tumor, including (a) a plastic tube having a cranial end and a caudal end, the plastic tube defining a main lumen for outflowing blood, two balloons, spaced apart about the plastic tube and bonded thereto for inflation thereabout, one being contiguous to the cranial end; wherein the balloons are sized and spaced on the plastic tube sufficient, that when inflated, they have sufficient size and spacing therebetween to substantially block the flow of blood in the vein and to substantially isolate outflow from the tumor to other portions of the vein; fenestrations in the plastic tube between the balloons to the main lumen; second and third lumina within the plastic tube; the second lumen connecting to one of the balloons; and, the third lumen connecting to the other of the balloons for effecting inflation or deflation of the balloons; the cranial end of the plastic tube being closed to substantially all inflow of blood. The method next includes: providing a second balloon catheter designed, sized and dimensioned for, in remaining part, isolating the area of the extremity by insertion into the specific artery or portion of the artery of the extremity feeding the blood to the tumor and for perfusing a chemotherapeutic agent into the area and tumor. The method next includes: perfusing the chemotherapeutic agent into the specific artery or portion of the artery through the second balloon catheter sufficient for effective therapeutic treatment of the tumor, withdrawing blood through the first catheter; and finally, recycling the blood from the withdrawing for reinfusion into the area and the tumor. The invention is applicable to any part of the body which can be described as an extremity, such as: an arm, a leg, a penis, a finger, a toe, a hand, a foot, a lower arm, or a lower leg. |
