| 发明名称 |
PHARMACEUTICALLY ACTIVE 3-ARYL AND 3-HETEROARYL-2-FLUORO-1-OLEFINS |
| 摘要 |
This invention relates to novel 3-aryl and 3-heteroaryl-2-fluoro-1-olefins of the formula (I) and their pharmacological use as dopamine beta-hydroxylase DBH inhibitors in the treatment of DBH mediated conditions such as hypertension. <IMG>
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| 申请公布号 |
CA2021547(C) |
申请公布日期 |
2000.10.24 |
| 申请号 |
CA19902021547 |
申请日期 |
1990.07.19 |
| 申请人 |
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发明人 |
MATTHEWS, DONALD P.;MCCARTHY, JAMES R.;BARNEY, CHARLOTTE L. |
| 分类号 |
A61K31/05;A61K31/047;A61K31/085;A61K31/38;A61K31/381;A61P9/12;A61P43/00;C07C17/00;C07C25/24;C07C37/62;C07C39/373;C07C41/22;C07C43/225;C07C391/02;C07D333/12;C07D333/28;(IPC1-7):C07C39/373;A61K31/055;C07C323/23 |
主分类号 |
A61K31/05 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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