摘要 |
Isothiazolones having the general structure where A is a monocyclic or bicyclic ring which may contain up to 3 heteroatoms selected from O, S, and N; R1 and R2 are substituent groups such as alkyl, alkoxy, hydroxy, nitro, cyano, amino, and carboxy; and R5 is alkyl, cycloalkyl, phenyl, and Het. The isothiazolones are useful as anti-retroviral agents, anti-inflammatory agents, and anti-atherosclerotic agents.
|
申请人 |
WARNER-LAMBERT COMPANY |
发明人 |
BOLTON, GARY LOUIS;DOMAGALA, JOHN MICHAEL;ELSLAGER, EDWARD FAITH;GOGLIOTTI, ROCCO DEAN;PURCHASE, TERRI STOEBER;SANCHEZ, JOSEPH PETER;TRIVEDI, BHARAT KALIDAS |