发明名称 NEW COMPOUND OF BENZYLAMINODIACETAMIDE FAMILY, AND COMPOSITION, PRODUCTION AND USE OF THE COMPOUND
摘要 <p>PROBLEM TO BE SOLVED: To obtain a new compound having good stimulation resistance and sedation properties, and useful for a composition intended to treat a too sensitive skin. SOLUTION: This new compound is the one of the formula R1 and R2 are each H, CH3 or the like; Z1 is NX1X2 or OX1; Z2 is NX3X4 or OX3 X1 and X3 are each a 1-12C alkyl [substituted with a 3-7C (heterocyclic) ring or the like] or an aryl; X2 and X4 are each H or form a 5- or 6-membered ring together with X1 or X3}}, e.g. 2-[(3,5-bis(trifluoromethyl)benzyl(hexylcarbamoylmethyl)amino-N-(3,4-d ichorophenyl)acetamide. The compound of the formula can be obtained by reacting a diacid with a dehydrating agent to provide an anhydride, and adding a coupling agent to the obtained anhydride. The compound can be formed into a composition such as an emulsion containing the compound of 0.001-20 wt.%.</p>
申请公布号 JP2000290252(A) 申请公布日期 2000.10.17
申请号 JP20000066441 申请日期 2000.03.10
申请人 L'OREAL SA 发明人 GALEY JEAN-BAPTISTE;DALKO MARIA
分类号 C07D295/16;A61K8/00;A61K8/02;A61K8/06;A61K8/30;A61K8/42;A61K8/49;A61K31/165;A61K31/167;A61K31/216;A61K31/4015;A61K31/4427;A61K31/4453;A61K31/4468;A61K31/451;A61K31/454;A61P17/00;A61P17/04;A61P17/16;A61P29/00;A61Q5/02;A61Q17/00;A61Q19/00;C07C237/04;C07C237/06;C07C237/20;C07C237/22;C07D207/26;C07D207/267;C07D207/27;C07D211/16;C07D211/58;C07D295/18;C07D295/185;C07D295/205;C07D401/04;C07D401/12;C07D401/14;(IPC1-7):C07D207/27;A61K7/00;A61K31/446;A61K31/445;A61K31/401;A61K7/48;A61K7/075 主分类号 C07D295/16
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