Novel method for manufacturing tricyclic amino alcohol derivatives

摘要

The present invention is directed to processes for the preparation of a compound useful for treating and preventing diabetes, obesity, hyperlipidemia and the like, which compound is represented by the formula (1) : wherein R<1> represents a lower alkyl group or a benzyl group; <*>1 represents an asymmetric carbon atom; R<2> represents a hydrogen atom, a halogen atom or a hydroxyl group; and A represents one of the following groups: wherein X represents NH, O or S; R<6> represents a hydrogen atom, a hydroxyl group, an amino group or an acetylamino group; and <*>2 represents an asymmetric carbon atom when R<6> is not a hydrogen atom, and to intermediates useful for the said processes. The processes of the present invention are convenient, practical preparing processes with low cost which comprise a small number of steps with good industrial work efficiency.