发明名称 Novel method for producing doxazosin mesylate in a crystalline modification designated as form
摘要 The invention relates to a method for producing doxazosin mesylate in the modification A. The method is characterised in that doxazosin and methane sulphonic acid are dissolved in a mixture containing an aprotic, polar organic solvent and methanol. Any clouding in the resulting solution is optionally eliminated. The clear solution thus produced is optionally injected with doxazosin mesylate crystals of form A, heated and isolated after the resulting product has been cooled. Said product is then washed with an organic solvent and dried.
申请公布号 AU3960800(A) 申请公布日期 2000.10.09
申请号 AU20000039608 申请日期 2000.03.06
申请人 KNOLL AKTIENGESELLSCHAFT 发明人 PETER KLEIN;MARCO THYES
分类号 A61K31/517;A61P9/12;C07D405/12 主分类号 A61K31/517
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