发明名称 IMPROVED CANCER TREATMENT WITH TEMOZOLOMIDE
摘要 <p>A method for treating a patient afflicted with cancer is provided, in which temozolomide is administered to the patient for at least two cycles of a cyclical dosing schedule, wherein each cycle has a dosing period of 5 to 25 days, in which temozolomide is administered daily, at a dose of 40 to 150 mg/m<2>/day, followed by a rest period of 5 to 14 days in which temozolomide is not administered. Also provided is a medical kit for administering temozolomide, having printed instructions for administering temozolomide according to the cyclical dosing schedule set forth above, and a supply of temozolomide in dosage units for at least one cycle, wherein each dosage unit contains 5 to 250 mg of temozolomide and a pharmaceutically acceptable carrier.</p>
申请公布号 WO0057867(A2) 申请公布日期 2000.10.05
申请号 WO2000US08079 申请日期 2000.03.27
申请人 SCHERING CORPORATION 发明人 RAGAB, MOHAMED, H.
分类号 C07D487/04;A61K31/41;A61K31/4188;A61P35/00;(IPC1-7):A61K31/00 主分类号 C07D487/04
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