PROSTAGLANDIN COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING PERIPHERAL VASCULAR DISEASE AND PULMONARY HYPERTENSION
摘要
Prostaglandin and analogs thereof which include protective groups attached to at least one site which are pharmaceutically acceptable and which are capable of slowing the metabolic rate of the active groups for administration to a warm blooded animal for the treatment of peripheral vascular disease and pulmonary hypertension. In fact, Figure 1 graphically shows the effects on pulmonary arterial pressure of a dose of mPEG20kDa-aminde-Compound X, given as an intravenous infusion to a sheep intravenously-induced with a pulmonary hypertensive agent.
申请公布号
WO0057701(A1)
申请公布日期
2000.10.05
申请号
WO2000US08240
申请日期
2000.03.29
申请人
UNITED THERAPEUTICS CORPORATION;SHORR, ROBERT;ROTHBLATT, MARTINE;BENTLEY, MICHAEL, D.;ZHAO, XUAN
发明人
SHORR, ROBERT;ROTHBLATT, MARTINE;BENTLEY, MICHAEL, D.;ZHAO, XUAN