发明名称 |
Z-STYRYL SULFONE ANTICANCER AGENTS |
摘要 |
(Z)-styryl benzylsulfones of formula (I) are useful as anticancer agents: wherein R1 is selected from the group consisting of hydrogen, chloro and nitro; R2 is selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, chloro, bromo, iodo and fluoro; and R3 and R4 are independently selected from the group consisting of hydrogen, lower akyl, nitro, chloro, bromo, iodo and fluoro; provided that at least one of R1 or R2 is hydrogen. The corresponding (Z)-styryl benzylsulfides are useful as intermediates in the preparation of the biologically active (Z)-styryl benzyl sulfones. |
申请公布号 |
WO0057872(A1) |
申请公布日期 |
2000.10.05 |
申请号 |
WO2000US08350 |
申请日期 |
2000.03.30 |
申请人 |
TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION;REDDY, E., PREMKUMAR;REDDY, M., V., RAMANA |
发明人 |
REDDY, E., PREMKUMAR;REDDY, M., V., RAMANA |
分类号 |
A61P35/00;A61K31/10;C07C317/10;C07C317/18;C07C321/20;C07C323/07 |
主分类号 |
A61P35/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|