发明名称 |
ANTIBODIES SPECIFIC FOR CYP1B1 |
摘要 |
Antibodies that can specially bind to cytochrome P450 CYP1B1 and methods of making them are disclosed, in particular antibodies that bind to amino acid sequence VNQWSVNHDPVKWPN or PExFDPARFLDKDGy, where x is D or N and y is L or F, or an antigenic fragment thereof. The antibodies can be used in the diagnosis or treatment of cancers linked to enhanced CYP1B1 expression, including breast cancer, prostate cancer, colorectal cancer, liver cancer and ovarian cancer.
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申请公布号 |
WO0056773(A1) |
申请公布日期 |
2000.09.28 |
申请号 |
WO2000GB01030 |
申请日期 |
2000.03.20 |
申请人 |
UNIVERSITY OF ABERDEEN;MELVIN, WILLIAM;MURRAY, GRAEME, IAN |
发明人 |
MELVIN, WILLIAM;MURRAY, GRAEME, IAN |
分类号 |
G01N33/53;A61K38/43;A61K39/395;A61K45/00;A61K47/02;A61K47/48;A61K51/00;A61P35/00;C07K14/80;C07K16/18;C07K16/40;C07K16/46;C12N9/02;C12N15/02;C12P21/08;G01N33/531;G01N33/574;G01N33/577;(IPC1-7):C07K16/40;C12N5/06;G01N33/573 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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