Improved powdery pharmaceutical compositions for inhalation

摘要

Compositions for use in dry powder inhalers contain a percentage of lubricant e.g. magnesium stearate to increase the fine particle dose. The highest possible surface area of the carrier particles is coated with the lubricant in order to increase the release of the active particles and hence the respirable fraction. A powder for use in a dry powder inhaler comprises an active ingredient and a carrier. The carrier includes between 0.05 and 0.5 percentage by weight of a lubricant. The lubricant particles at least partially coat the carrier particles surface.