| 摘要 |
<p>A bacterial protein conjugated to small antigenic determinants such as peptides or other small haptens. The bacterial protein that is used in the present invention is bacterial flagella. The flagella may be derived from any flagellated microorganisms; however, those from Salmonella species are preferred. The bacterial flagella can be in the native polymerized form or can be repolymerized flagellin. The vaccine is especially effective for vaccinating a human or animal against a peptide or other small hapten. The improved vaccine provides a prolonged and potent immune response against the peptide or other small hapten.</p> |
