发明名称 IMMUNOMODULATOR AND PHARMACEUTICAL COMPOSITIONS WITH ANTITUMOR PROPERTIES, AND A FOOD ADDITIVE
摘要 The invention proposes the use of alpha and/or beta -glycosides N-acetylmuramil-L-alanyl-D-isoglutamine /CH3-/CH2/n-muramildipeptide (MDP) as an immunomodulator, as well as pharmaceutical compositions with antitumor properties that include an effective quantity of alpha and/or beta -glycosides muramildipeptide (MDP) and physiologically acceptable carriers. The dosage of the active ingredient in the form of a drug is of 0.0001-100 mg/kg in weight when administered perorally, of 0.00001-30 mg/kg in weight when administered intravenously, and of 0.00001-10 mg/kg in weight in the case of a lyposomal administration. This invention also relates to a preparation formulated on the basis of alpha and/or beta -glycosides MDP/CH3-/CH2/n-MDP/ which activates the main immunity bonds. The invention further proposes the use of alpha and/or beta -glycosides N-acetylmuramil-L-alanyl-D-isoglutamine as a food additive.
申请公布号 EP1038532(A1) 申请公布日期 2000.09.27
申请号 EP19980920755 申请日期 1998.04.09
申请人 KALJUZHIN, OLEG VITALLIEVICH;SHKALEV, MIKHAIL VLADIMIROVICH 发明人 KALJUZHIN, OLEG VITALLIEVICH;SHKALEV, MIKHAIL VLADIMIROVICH
分类号 A23L1/305;A61K38/05;A61K38/14 主分类号 A23L1/305
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