发明名称 Stabilization of isothiazolone
摘要 The present invention provides a highly stable formulation having broad spectrum preservative properties. The formulation is an admixture of dialkanol-substituted dimethyhydantoin, one or more isothiazolone compounds, a hydantoin stabilizer, and a hydroxyl solvent. The formulation is highly stable in pH ranges of about 4 to 8. Preferably the active components are dimethyloldimethylhydantoin, chloromethylisothiazolone and methylisothiazolone, and the stabilizer dimethylhydantoin. The formulation has a free formaldehyde content of less than 0.2% and is beneficial for preserving various aqueous compositions, including household and industrial products, and especially personal care products, which require a less acidic pH range than in which isothiazolone is stable in the presence of cationic salts.
申请公布号 US6121302(A) 申请公布日期 2000.09.19
申请号 US19990309686 申请日期 1999.05.11
申请人 LONZA, INC. 发明人 ROTHENBURGER, STEPHEN JUDE;HIGBEE, VALERIE LYNN;LUTZ, PATRICK JAY
分类号 A61K8/00;A01N43/80;A61K8/49;A61K31/425;A61K47/22;A61Q5/02;A61Q19/10;(IPC1-7):A61K31/425 主分类号 A61K8/00
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