| 摘要 |
PROBLEM TO BE SOLVED: To obtain the subject cosmetic having no skin irritation, excellent inhibitory effect on skin inflammation by ultraviolet light, inhibiting effect on melanization and rapidly hypochromic effect on skin pigmentation by making the cosmetic include a specific hydroxyketone compound. SOLUTION: This cosmetic contains at least one selected from 3-hydroxy ketone compounds of the formula (R1 is H, CH3 or C2H5; each aromatic group is substituted with 1-3 OR1 groups) (hereinafter PHPO). For example, 1,5-bis(p- hydroxyphenyl)-2-hydroxypentan-4-one, etc., may be cited as the PHPO. The compound is obtained by synthesizing a 2-isoxazoline compound from an aryl acedoxime compound and an allylarene by using NaOCl and triethylamine and reducing the 2-isoxazoline compound with a Raney-Ni. The formulation amount in the bleaching cosmetic is preferably 0.001-5.0 wt.% based on the total amount.
|
