发明名称 |
Phosphate and thiophosphate protecting groups |
摘要 |
Novel phosphorus protecting groups, intermediates thereof, and synthetic processes for making the same are disclosed. Oligomeric compounds are prepared through the protection of one or more internucleosidic phosphorus functionalities, preferably followed by oxidation and cleavage of the protecting groups to provide oligonucleotides.
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申请公布号 |
US6121437(A) |
申请公布日期 |
2000.09.19 |
申请号 |
US19990268797 |
申请日期 |
1999.03.16 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
GUZAEV, ANDREI P.;MANOHARAN, MUTHIAH |
分类号 |
C07H19/10;C07H19/20;C07H21/00;(IPC1-7):C07H19/04;C07H1/00 |
主分类号 |
C07H19/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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