| 摘要 |
This invention relates to isoxazoline compounds which are inhibitors of 5-lipoxygenase (5-LO). The isoxazoline compounds are useful in the treatment or alleviation of inflammatory disease, allergy and cardiovascular diseases, wherein the inflammatory disease or condition is asthma, arthritis, bronchitis, chronic obstructive pulmonary disease, psoriasis, allergic rhinitis, dermatitis, shock, atopic dermatitis rheumatoid arthritis and osteoarthritis. This invention also relates to pharmaceutical compositions useful therefor.
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