| 发明名称 |
C16 UNSATURATED FP-SELECTIVE PROSTAGLANDINS ANALOGS |
| 摘要 |
The invention provides novel PGF analogs. In particular, the present inventi on relates to compounds having a structure according to formula (I) wherein R1, X, and Z are defined below. This invention also includes optical isomers, diastereomers and enantiomers of said formula, and pharmaceutically-acceptab le salts, biohydrolyzable amides, esters, and imides thereof. The compounds of the present invention are useful for the treatment of a variety of diseases and conditions, such as bone disorders. Accordingly, the invention further provides pharmaceutical compositions comprising these compounds. The inventi on still further provides methods of treatment for bone disorders using these compounds or the compositions containing them.
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| 申请公布号 |
CA2364944(A1) |
申请公布日期 |
2000.09.08 |
| 申请号 |
CA20002364944 |
申请日期 |
2000.02.29 |
| 申请人 |
THE PROCTER & GAMBLE COMPANY |
发明人 |
DE, BISWANATH;WOS, JOHN AUGUST;DELONG, MITCHELL ANTHONY;SOPER, DAVID LINDSEY |
| 分类号 |
A61K31/557;A61K31/5575;A61P1/00;A61P9/12;A61P13/10;A61P15/00;A61P17/00;A61P19/00;A61P19/08;A61P19/10;A61P27/02;A61P27/06;A61P27/16;C07B53/00;C07C;C07C59/215;C07C59/56;C07C59/72;C07C235/26;C07C251/06;C07C259/06;C07C311/51;C07C327/22;C07C405/00;C07D277/64;C07D307/40;C07D307/46;C07D307/54;C07D307/66;C07D307/80;C07D333/36;C07D333/56;C07D333/60;(IPC1-7):C07C405/00 |
主分类号 |
A61K31/557 |
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