摘要 |
The present invention is directed to compounds of Formula I:
wherein X represents cis - or trans- alkenyl group represented by -(CH=CH) 1 -; each of R 1 , R 2 , R 3 and R 4 is H or Q + , while at least one of R 1 , R 2 , R 3 and R 4 is Q + ; and Q + is a sodium, piperazine, or nicotinamide cation. The invention also relates to pharmaceutical compositions comprising these compounds. The compounds of the invention can be used for the treatment of neoplastic disease. |