发明名称 Compositions and methods for use in targeting vascular destruction
摘要 The present invention is directed to compounds of Formula I: wherein X represents cis - or trans- alkenyl group represented by -(CH=CH) 1 -; each of R 1 , R 2 , R 3 and R 4 is H or Q + , while at least one of R 1 , R 2 , R 3 and R 4 is Q + ; and Q + is a sodium, piperazine, or nicotinamide cation. The invention also relates to pharmaceutical compositions comprising these compounds. The compounds of the invention can be used for the treatment of neoplastic disease.
申请公布号 AU3597300(A) 申请公布日期 2000.09.04
申请号 AU20000035973 申请日期 2000.02.16
申请人 OXI-GENE, INC. 发明人 RONALD W. PERO;DAVID SHERRIS
分类号 A61K45/00;A61K;A61K31/05;A61K31/135;A61K31/136;A61K31/38;A61K31/381;A61K31/40;A61K31/404;A61K31/66;A61K31/661;A61K31/6615;A61K31/664;A61K31/665;A61K31/67;A61K31/683;A61P9/00;A61P35/00;C07D209/12;C07D333/56;C12Q1/02 主分类号 A61K45/00
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