| 摘要 |
An electro-dose constitutes a metered medical powder and is formed from an electro-powder constituting an active powder substance or a dry powder medical formulation being transferred onto a device member forming a dose carrier. The electro-dose prepared from an electro-powder presents a fine particle fraction (FPF) having of the order 50% or more of its content with a particle size between 0.5-5 mum. The electro-powder of such a metered electro-dose further provides electrostatic properties regarding absolute specific charge per mass after charging of the order 0.1 to 25 muC/g and presents a charge decay rate constant Q50 of more than 0.1 sec with a tap density of less than 0.8 g/ml and a water activity aw of less than 0.5. The electro-dose porosity is adjusted to obtain an optimized porosity value in percent of 75 to 99.9 calculated as 100-100x(Densityelectro-dose/Densityelectro-powder). |
