TUMOR NECROSIS FACTOR ANTAGONISTS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS

摘要

A method for inhibiting the action of TNF for treating neurological conditio ns in a human by administering a TNF antagonist for reducing damage to neuronal tissue or for modulating the immune response affecting neuronal tissue of th e human. The TNF antagonist administered is selected from the group consisting of etanercept and infliximab. The TNF antagonist is administered subcutaneously, intravenously, intrathecally, or intramuscularly. Methotrexa te or Leflunomide may be administered concurrently with the TNF antagonist for demyelinating diseases and certain other neurological disorders.