发明名称 PROCESS FOR THE PRODUCTION OF TERT-BUTYL (E)-(6-[2- [4-(4-FLUOROPHENYL) -6-ISOPROPYL-2-[ METHYL (METHYLSULFONYL) AMINO] PYRIMIDIN-5-YL] VINYL](4R, 6S)-2,2-DIMETHYL [1,3]DIOXAN-4-YL) ACETATE
摘要 <p>The invention concerns a process for the manufacture of <u>tert</u>-butyl (E)-(6-[2- 4-(4-fluorophenyl) -6-isopropyl-2-[ methyl (met hylsulfonyl) amino] pyrimidin-5-yl] vinyl}-(4R, 6S)-2,2-dimethyl [1,3-dioxan-4-yl) acetate, the novel starting material used in said process and the use of the process in the manufacture of a pharmaceutical.</p>
申请公布号 WO0049014(A1) 申请公布日期 2000.08.24
申请号 WO2000GB00481 申请日期 2000.02.15
申请人 ASTRAZENECA UK LIMITED;SHIONOGI & CO. LTD.;KOIKE, HARUO;KABAKI, MIKIO;TAYLOR, NIGEL, PHILIP;DIORAZIO, LOUIS, JOSEPH 发明人 KOIKE, HARUO;KABAKI, MIKIO;TAYLOR, NIGEL, PHILIP;DIORAZIO, LOUIS, JOSEPH
分类号 A61K31/505;A61P3/06;A61P9/00;A61P9/10;C07D239/00;C07D239/42;C07D319/06;C07D319/08;C07D405/06;C07F9/53;C07F9/6512;(IPC1-7):C07D405/06 主分类号 A61K31/505
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