| 摘要 |
medicine, endocrinology, pharmacy. SUBSTANCE: pharmaceutical composition has effective amounts of 6-unsaturated fatty acid and substance that decreases sorbitol intracellular level in body. Gamma-linolenic acid, dihomo-gamma-linolenic acid or arachidonic acid can be used as 6-unsaturated fatty acid. Inhibitor of aldose reductase can be used as substance decreasing sorbitol level in the body. Method of prophylaxis and treatment of patients with diabetes mellitus complications involves administration in body of effective amounts of composition or its components under condition of their simultaneous presence in the body making. Invention ensures to use natural substances that are known as tolerant ones used in large doses. EFFECT: enhanced effectiveness of treatment, decreased risk of adverse effects. 7 cl, 3 dwg, 12 ex
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