摘要 |
<p>A biological method of making a compound having formula (I), wherein R1 is CH=CH¿2?, COOH, CH2-CH3 or OH; R?3¿ is OH, or -OCH¿3; R?4 is OH; and R?2, R5 and R6¿ are hydrogen, comprises treating a substrate comprising at least 0.5 % on a dry weight basis of a compound of formula (II), wherein R1 is CH=CH-COOH; and R?2, R3, R4, R5 and R6¿ are as defined above, with one or more fungus (including yeast) microorganisms in viable or non-viable forms and/or an enzymic and/or cell free extract and/or engineered enzyme or cell derived from said microorganisms.</p> |