METHOD FOR DIAGNOSING PROLIFERATION REGIONS AND DEVICE FOR REALISING THE SAME

摘要

The present invention relates to a non-invasive and contactless method for diagnosing in vivo in a living organism the regions of biological tissue proliferation as well as their localisation areas by visualising the fluorescence of endogenous porphyrins. This invention also relates to a device for realising this method. The tissues are illuminated with a low-intensity monochromatic radiation having a wavelength of 630 to 645 nm, and the fluorescent image is subsequently recorded in a range of 650 to 730 nm, wherein the recording is carried out in one or more cycles. The method further involves averaging the brightness values of the corresponding points of the images for all the recording cycles, determining the significant range of the brightness values for the averaged image, and spreading this range by scaling onto the whole dynamic range of the display device. The method further involves recording at the same angle and the same scale a reference colour image of the tissues, secondary images at the excitation wavelength and at the fluorescence wavelength by illumination from corresponding sources, as well as fluorescent images of the natural proliferation region in the same patient and of the iridescent test object. The device for realising this method further includes an additional illumination source for the test premises.