METHOD FOR THE RACEMIZATION OF OPTICALLY ACTIVE AMINES

摘要

The invention relates to a method for producing racemic amines of formula (I), in which R<1> and R<2> are not the same and R<1>, R<2>, R<3> are alkyl-, cycloalkyl-, arylalkyl-, aryl-, heteroaryl rests and heterocyclic rests and R<3> also represents hydrogen. Said rests can carry substituents selected from the group of alkyl, cycloalkyl, alkoxy, aryloxy, amino, alkylamino and dialkylamino. The method is characterized in that the corresponding optically active amine (I) and the secondary alcohol of formula (II) and/or the asymmetrical ketone of formula (III) and the amine of the formula R<3>NH2 are simultaneously reacted in situ in the presence of hydrogen and a hydrogenation or dehydrogenation catalyst at an elevated temperature.