| 发明名称 |
METHOD OF PREPARING MEDICINAL FORM OF ISONIAZIDE SHOWING DECREASED HEPATOTOXICITY |
| 摘要 |
pharmaceutical industry. SUBSTANCE: isoniazide is mixed with beet pectin and sucrose in the ratio 1:6:1. 40-% ethyl alcohol is added to total mixture amount in parts as a moistening agent up to formation of mass to be granulated. Obtained granules are treated with 10% solution of calcium chloride and dried at 60 ± 5 C for 1 h. EFFECT: decreased hepatotoxicity, retained tuberculostatic activity of agent. 1 dwg, 6 tbl
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| 申请公布号 |
RU2153878(C1) |
申请公布日期 |
2000.08.10 |
| 申请号 |
RU19990109344 |
申请日期 |
1999.04.27 |
| 申请人 |
PJATIGORSKAJA GOSUDARSTVENNAJA FARMATSEVTICHESKAJA;PJATIGORSKAJA G FARMATSEVTICHE |
发明人 |
SADZHAJA L.A.;VASILENKO JU.K.;KOMPANTSEVA E.V.;MOSKALENKO S.V.;FROLOVA L.M.;PARFENT'EVA E.P. |
| 分类号 |
A61K31/732;A61K9/16;A61K31/455;A61K31/70;A61K33/14;A61P31/06;(IPC1-7):A61K31/732 |
主分类号 |
A61K31/732 |
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