| 摘要 |
Aminoacetic acid esters of formula I in which R1, R2 and R3 are identical or different hydrocarbon radicals, or any two of these radicals form a carbon ring with the carbon atom to which they are attached and R4 is hydrogen or an alkyl radical having 1-4 carbon atoms, are prepared by reacting an alpha -substituted malonic acid monoamide ester of formula II wherein R1, R2, R3 and R4 have the meanings above, by the Hofmann degradation reaction, with a hypohalite in an amount of up to 1.5 equivalents in an aqueous-basic medium containing base in an amount of 0.8-1.5 equivalents per mol. of starting malonic acid monoamide ester II.
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