发明名称 |
Electrophoretic assays to assess conformational changes of integrins induced by ligand binding |
摘要 |
This invention relates to electrophoretic assays useful for the detection of conformational changes in integrin structure upon binding of antagonists, agonists or ligands. Such assays are useful to identify drug candidate compounds that may have a high potential for side reactions when administered in patients. |
申请公布号 |
AU3349900(A) |
申请公布日期 |
2000.08.07 |
申请号 |
AU20000033499 |
申请日期 |
2000.01.26 |
申请人 |
DU PONT PHARMACEUTICALS COMPANY |
发明人 |
RICHARD WYNN;NINA I. ZOLOTARARJOVA |
分类号 |
C02F1/469;G01N33/53;G01N33/561;G01N33/566;G01N33/567 |
主分类号 |
C02F1/469 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|