发明名称 |
DERIVE D'ACIDE PYRAZOLECARBOXYLIQUE, SA PREPARATION, LES COMPOSITIONS PHARMACEUTIQUES EN CONTENANT |
摘要 |
The invention concerns N-piperidino-5-(4-bromophenyl)-1-(2,4dichlorophenyl)-4-ethylpyrazole-3 -carboxamide, the salts and solvents thereof which are powerful antagonists of cannabinoid CB1 receptors. The method for preparing them consists in reacting a functional derivative of 5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-ethylpyrazole-3-carboxylic acid with 1-aminopiperidine with subsequent optional salification.
|
申请公布号 |
FR2789079(A1) |
申请公布日期 |
2000.08.04 |
申请号 |
FR19990010166 |
申请日期 |
1999.08.02 |
申请人 |
SANOFI-SYNTHELABO |
发明人 |
BARTH FRANCIS;CAMUS PHILIPPE;MARTINEZ SERGE;RINALDI MURIELLE |
分类号 |
A61K31/415;A61K31/454;A61P3/00;A61P3/04;A61P25/00;A61P25/18;A61P25/28;A61P25/32;A61P25/34;A61P43/00;C07C69/738;C07C251/80;C07D231/14;(IPC1-7):C07D401/12;C07C251/76;C07C69/007;A61K31/216;A61K31/15 |
主分类号 |
A61K31/415 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|