发明名称 DERIVE D'ACIDE PYRAZOLECARBOXYLIQUE, SA PREPARATION, LES COMPOSITIONS PHARMACEUTIQUES EN CONTENANT
摘要 The invention concerns N-piperidino-5-(4-bromophenyl)-1-(2,4dichlorophenyl)-4-ethylpyrazole-3 -carboxamide, the salts and solvents thereof which are powerful antagonists of cannabinoid CB1 receptors. The method for preparing them consists in reacting a functional derivative of 5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-ethylpyrazole-3-carboxylic acid with 1-aminopiperidine with subsequent optional salification.
申请公布号 FR2789079(A1) 申请公布日期 2000.08.04
申请号 FR19990010166 申请日期 1999.08.02
申请人 SANOFI-SYNTHELABO 发明人 BARTH FRANCIS;CAMUS PHILIPPE;MARTINEZ SERGE;RINALDI MURIELLE
分类号 A61K31/415;A61K31/454;A61P3/00;A61P3/04;A61P25/00;A61P25/18;A61P25/28;A61P25/32;A61P25/34;A61P43/00;C07C69/738;C07C251/80;C07D231/14;(IPC1-7):C07D401/12;C07C251/76;C07C69/007;A61K31/216;A61K31/15 主分类号 A61K31/415
代理机构 代理人
主权项
地址