摘要 |
The present invention relates to immunological adjuvants. In particular, it relates to Mycobacterium tuberculosis proteins which stimulate interleukin-12 (IL-12) and interferon gamma production. These proteins and fragments thereof may be used in combination with an antigen for inducing and/or enhancing an immune response to the antigen. Alternatively, polynucleotides encoding such proteins may be ligated with an antigen coding sequence to produce a fusion protein as an immunogen. |