发明名称 [r-(z)]-alpha-(methoxyimino)-alpha-(1-azabicyclo[2.2.2]oct-3-yl) acetonitrile for reducing amyloid beta a4 formation in alzheimer's disease
摘要 This method of enhancing amyloid precursor protein processing along a non-amyloidogenic pathway in patients suffering from, or at risk of developing, Alzheimer's disease, by reducing bA4 production in patients suffering from, or at risk of developing, Alzheimer's disease comprising administering to the patient an effective, non-toxic amount of the acetonitrile compound [R-(Z)]-a-(methoxyimimo)-a-(1-azabicyclo[2.2.2]oct-3-yl)acetonitrile.
申请公布号 NZ295155(A) 申请公布日期 2000.07.28
申请号 NZ19950295155 申请日期 1995.10.17
申请人 SMITHKLINE BEECHAM PLC 发明人 MARKWELL, ROGER EDWARD;HAWKINS, JULIE;GRAY, CAROL WENDY
分类号 C07D453/02;A61K31/435;A61K31/439;A61P25/28;(IPC1-7):A61K31/435 主分类号 C07D453/02
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