发明名称 |
[r-(z)]-alpha-(methoxyimino)-alpha-(1-azabicyclo[2.2.2]oct-3-yl) acetonitrile for reducing amyloid beta a4 formation in alzheimer's disease |
摘要 |
This method of enhancing amyloid precursor protein processing along a non-amyloidogenic pathway in patients suffering from, or at risk of developing, Alzheimer's disease, by reducing bA4 production in patients suffering from, or at risk of developing, Alzheimer's disease comprising administering to the patient an effective, non-toxic amount of the acetonitrile compound [R-(Z)]-a-(methoxyimimo)-a-(1-azabicyclo[2.2.2]oct-3-yl)acetonitrile.
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申请公布号 |
NZ295155(A) |
申请公布日期 |
2000.07.28 |
申请号 |
NZ19950295155 |
申请日期 |
1995.10.17 |
申请人 |
SMITHKLINE BEECHAM PLC |
发明人 |
MARKWELL, ROGER EDWARD;HAWKINS, JULIE;GRAY, CAROL WENDY |
分类号 |
C07D453/02;A61K31/435;A61K31/439;A61P25/28;(IPC1-7):A61K31/435 |
主分类号 |
C07D453/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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