| 摘要 |
<p>Quickly soluble solid preparations which quickly disintegrate and dissolve in administration sites with limited moisture content, for example, in the oral cavity. One of the dosage forms thereof is a solid preparation obtained by mixing drugs with saccharides which are soluble at a ratio of 30 g or less in 100 g of water at room temperature, saccharides which are soluble at a ratio of 30 g or more in 100 g of water at room temperature, and water in such an amount that the former saccharides cannot be completely dissolved therein, followed by the elimination of the moisture. Other dosage forms thereof include a solid preparation obtained by dissolving/dispersing drugs, saccharides and polyvinyl pyrrolidone in an organic solvent followed by the elimination of the organic solvent, and another solid preparation obtained by dissolving and/or dispersing drugs in an aqueous solution of saccharides followed by freeze-drying. Because of rapidly soluble in the oral cavity, these preparations are easy to take for patients with deglutition disorder, the aged and infants, which brings about expectations of improvement in the compliance.</p> |
