摘要 |
PURPOSE: Provided is a combination therapy for treatment of psychoses. CONSTITUTION: A method for treating a patient suffering from or susceptible to psychosis, acute mania, mild anxiety states, or depression in combination with psychotic episodes, comprising administering to the patient an effective amount of a first component which is an atypical antipsychotic, in combination with an effective amount of a second component which is a serotonin reuptake inhibitor. The first component is chosen from the group consisting of olanzapine, clozapine, risperidone, sertindole, quetiapine, and ziprasidone; and the second component is selected from the group consisting of fluoxetine, venlafaxine, citalopram, fluvoxamine, paroxetine, sertraline, milnacipran and duloxetine. Wherein the first component compound is 0.25-50 mg preferably, 1-30 mg of olanzapine and the second component compound is 10-40 mg preferably, 20-80 mg of fluoxetine. Administration of the compounds is oral.
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