发明名称 COMBINATION THERAPY FOR TREATMENT OF PSYCHOSES
摘要 PURPOSE: Provided is a combination therapy for treatment of psychoses. CONSTITUTION: A method for treating a patient suffering from or susceptible to psychosis, acute mania, mild anxiety states, or depression in combination with psychotic episodes, comprising administering to the patient an effective amount of a first component which is an atypical antipsychotic, in combination with an effective amount of a second component which is a serotonin reuptake inhibitor. The first component is chosen from the group consisting of olanzapine, clozapine, risperidone, sertindole, quetiapine, and ziprasidone; and the second component is selected from the group consisting of fluoxetine, venlafaxine, citalopram, fluvoxamine, paroxetine, sertraline, milnacipran and duloxetine. Wherein the first component compound is 0.25-50 mg preferably, 1-30 mg of olanzapine and the second component compound is 10-40 mg preferably, 20-80 mg of fluoxetine. Administration of the compounds is oral.
申请公布号 KR20000048518(A) 申请公布日期 2000.07.25
申请号 KR19997002422 申请日期 1999.03.22
申请人 ELI LILLY AND COMPANY 发明人 BYMASTER FRANKLIN PORTER;PERRY KENNETH WAYNE;TOLLEFSON GARY DENNIS
分类号 A61K31/135;A61K31/137;A61K31/15;A61K31/165;A61K31/343;A61K31/381;A61K31/415;A61K31/445;A61K31/451;A61K31/4525;A61K31/4545;A61K31/495;A61K31/496;A61K31/505;A61K31/519;A61K31/55;A61K31/551;A61K31/554;A61K45/06;A61P25/18;(IPC1-7):A61K31/55 主分类号 A61K31/135
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